High-dose methotrexate is the backbone of various regimens DIL Switches for treating lymphoid malignancies.Mucositis is a well-known, dose-related side effect of methotrexate.Prophylactic measures such as folinic acid rescue are useful but do not prevent mucositis in all the cases.Once severe mucositis (WHO Grade IV) sets in, mortality is very high
Artifacts play an essential role in the contours of a cultural tradition, constituting the constant landmarks of a perennial.Within a given cultural horizon, those artifacts that express the ethos of that horizon in an exemplary way are the most important.In most cases, the artifacts embody symbolic codes and forms belonging to the original, coagul
Traditional knowledge concerning plant utilization in the Philippines is common but is largely underappreciated.Assessment of plant resources by groups of people helps promote valorization of cultural heritage.However, particularly in the Camiguin Is-landof the North, Cagayan (not to be confused with the island province of Camiguin in Mindanao), th
Rudolf Engelhard presents a lesson model in his article How to Deal with Party Politics at School? that dates back to the 1960s, Universal Microswitch Kit when civic education was revived in the Federal Republic of Germany (West-Germany).In order to improve civic education at school, the former Ministers of Education of German states reached a join